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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
12.42
Human Site:
S622
Identified Species:
27.33
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
S622
T
N
L
D
F
F
Q
S
D
P
F
V
G
S
D
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
S622
T
N
L
D
F
F
Q
S
D
P
F
V
G
S
D
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
N749
F
K
G
D
P
F
Q
N
D
P
F
A
E
Q
Q
Dog
Lupus familis
XP_532580
889
97932
Q609
D
T
N
L
D
F
F
Q
S
D
P
F
V
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
Q621
D
T
N
L
D
F
F
Q
S
D
P
F
V
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
S646
T
S
L
E
F
F
Q
S
D
P
F
V
G
S
D
Frog
Xenopus laevis
O42287
1270
143652
E666
Q
D
R
V
K
Q
E
E
E
R
Y
K
F
Q
D
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
S711
P
G
L
D
F
F
Q
S
D
P
F
T
D
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
P665
E
S
P
S
P
A
L
P
P
K
K
A
K
Q
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
A781
F
K
S
E
A
F
Q
A
N
P
F
G
G
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
E988
T
A
N
P
N
L
T
E
T
L
S
D
R
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
40
6.6
N.A.
6.6
N.A.
N.A.
N.A.
86.6
6.6
73.3
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
100
46.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
100
33.3
73.3
N.A.
N.A.
6.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
10
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
10
0
37
19
0
0
0
46
19
0
10
10
10
55
% D
% Glu:
10
0
0
19
0
0
10
19
10
0
0
0
10
0
0
% E
% Phe:
19
0
0
0
37
73
19
0
0
0
55
19
10
10
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
0
10
37
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
10
0
0
0
0
10
10
10
10
0
0
% K
% Leu:
0
0
37
19
0
10
10
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
28
0
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
0
10
10
19
0
0
10
10
55
19
0
0
0
19
% P
% Gln:
10
0
0
0
0
10
55
19
0
0
0
0
0
28
10
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
19
10
10
0
0
0
37
19
0
10
0
0
37
19
% S
% Thr:
37
19
0
0
0
0
10
0
10
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
28
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _